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Ductile extension of 3-D external circumferential cracks in pipe structures
Wuchao YANG, Xudong QIAN
Frontiers of Structural and Civil Engineering 2011, Volume 5, Issue 3, Pages 294-303 doi: 10.1007/s11709-011-0115-9
Keywords:
ductile fracture
computational cell method
G-T model
Novel mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient
Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 150-155 doi: 10.1007/s11684-021-0846-5
Keywords: cystic fibrosis CFTR splicing mutation minigene
Ensemble unit and AI techniques for prediction of rock strain
Pradeep T; Pijush SAMUI; Navid KARDANI; Panagiotis G ASTERIS
Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 7, Pages 858-870 doi: 10.1007/s11709-022-0831-3
Keywords: prediction strain ensemble unit rank analysis error matrix
Sustainable intensification of agriculture in Africa
Antonius G.T. SCHUT, Ken E. GILLER
Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 4, Pages 371-375 doi: 10.15302/J-FASE-2020357
Keywords: Green Revolution Manihot esculenta Musa acuminata sub-Saharan Africa
PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa
Frontiers of Medicine 2008, Volume 2, Issue 3, Pages 259-263 doi: 10.1007/s11684-008-0049-3
REINTEGRATION OF CROP-LIVESTOCK SYSTEMS IN EUROPE: AN OVERVIEW
Antonius G. T. SCHUT, Emily C. COOLEDGE, Marc MORAINE, Gerrie W. J. VAN DE VEN, Davey L.
Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 1, Pages 111-129 doi: 10.15302/J-FASE-2020373
Keywords: circular agriculture coupled farming systems mixed farming specialised farming systems GHG
G. X. WANG, X. R. WEI, V. RUDOLPH, C. T. WEI, Y. QIN
Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 1, Pages 20-25 doi: 10.1007/s11705-009-0138-0
Keywords: multi-scale model gas transport coal coalbed methane CO2 sequestration
Peter T. Cummings, Philippe M. Fauchet, Michael Goldfarb, Martha W.M.Perlin, Nilanjan Sarkar, Keivan G. Stassun, Zachary E. Warren, Karl E. Zelik
Engineering 2021, Volume 7, Issue 2, Pages 141-143 doi: 10.1016/j.eng.2020.06.020
Lyle Hood,Rudy T. Andriani,Tobias E. Ecker,John L. Robertson,Christopher G. Rylander
Engineering 2015, Volume 1, Issue 3, Pages 344-350 doi: 10.15302/J-ENG-2015077
Keywords: near-infrared laser thermochemotherapy agarose photothermal heating micro-catheter malignant glioma
State-of-the-art of intelligent minimally invasive surgical robots
Masakatsu G. Fujie, Bo Zhang
Frontiers of Medicine 2020, Volume 14, Issue 4, Pages 404-416 doi: 10.1007/s11684-020-0743-3
Keywords: robot history medical robot surgical robot radiofrequency ablation organ model
Predictive Functional Control Based on Fuzzy Model for HVAC Systems
Lu Hongli,Jia Lei,Wang Lei,Gao Rui
Strategic Study of CAE 2006, Volume 8, Issue 9, Pages 65-68
Keywords: T-S fuzzy model predictive functional control least squares method HVAC systems
R158Q and G212S, novel pathogenic compound heterozygous variants in of Gitelman syndrome
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 932-945 doi: 10.1007/s11684-022-0963-9
Keywords: Gitelman syndrome mouse model compound heterozygous hypokalemia Slc12a3
Hongyuan Zhang, Yifei Zhang, Wei-Xiao Wang, Weizhong Chen, Xia Zhang, Xingxu Huang, Wei Chen, Quanjiang Ji
Engineering 2022, Volume 15, Issue 8, Pages 67-77 doi: 10.1016/j.eng.2022.02.013
Keywords: CRISPR Cas9 Mycobacterium tuberculosis Genome editing Base editing
Manikandan, T. Viruthagiri
Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 3, Pages 240-249 doi: 10.1007/s11705-009-0205-6
Keywords: and fermentation (SSF) starch coculture fermentation statistical experimental design bioethanol Monod model
Optimal Antibody Purification Strategies Using Data-Driven Models Article
Songsong Liu, Lazaros G. Papageorgiou
Engineering 2019, Volume 5, Issue 6, Pages 1077-1092 doi: 10.1016/j.eng.2019.10.011
This work addresses the multiscale optimization of the purification processes of antibody fragments. Chromatography decisions in the manufacturing processes are optimized, including the number of chromatography columns and their sizes, the number of cycles per batch, and the operational flow velocities. Data-driven models of chromatography throughput are developed considering loaded mass, flow velocity, and column bed height as the inputs, using manufacturing-scale simulated datasets based on microscale experimental data. The piecewise linear regression modeling method is adapted due to its simplicity and better prediction accuracy in comparison with other methods. Two alternative mixed-integer nonlinear programming (MINLP) models are proposed to minimize the total cost of goods per gram of the antibody purification process, incorporating the data-driven models. These MINLP models are then reformulated as mixed-integer linear programming (MILP) models using linearization techniques and multiparametric disaggregation. Two industrially relevant cases with different chromatography column size alternatives are investigated to demonstrate the applicability of the proposed models.
Keywords: purification Multiscale optimization Antigen-binding fragment Mixed-integer programming Data-driven model
Title Author Date Type Operation
Ductile extension of 3-D external circumferential cracks in pipe structures
Wuchao YANG, Xudong QIAN
Journal Article
Novel mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient
Journal Article
Ensemble unit and AI techniques for prediction of rock strain
Pradeep T; Pijush SAMUI; Navid KARDANI; Panagiotis G ASTERIS
Journal Article
Sustainable intensification of agriculture in Africa
Antonius G.T. SCHUT, Ken E. GILLER
Journal Article
randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against recurrence of T1G3
PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa
Journal Article
REINTEGRATION OF CROP-LIVESTOCK SYSTEMS IN EUROPE: AN OVERVIEW
Antonius G. T. SCHUT, Emily C. COOLEDGE, Marc MORAINE, Gerrie W. J. VAN DE VEN, Davey L.
Journal Article
Engineering for Inclusion: Empowering Individuals with Physical and Neurological Differences through Engineering Invention, Research, and Development
Peter T. Cummings, Philippe M. Fauchet, Michael Goldfarb, Martha W.M.Perlin, Nilanjan Sarkar, Keivan G. Stassun, Zachary E. Warren, Karl E. Zelik
Journal Article
Characterizing Thermal Augmentation of Convection-Enhanced Drug Delivery with the Fiberoptic Microneedle Device
Lyle Hood,Rudy T. Andriani,Tobias E. Ecker,John L. Robertson,Christopher G. Rylander
Journal Article
State-of-the-art of intelligent minimally invasive surgical robots
Masakatsu G. Fujie, Bo Zhang
Journal Article
Predictive Functional Control Based on Fuzzy Model for HVAC Systems
Lu Hongli,Jia Lei,Wang Lei,Gao Rui
Journal Article
R158Q and G212S, novel pathogenic compound heterozygous variants in of Gitelman syndrome
Journal Article
PAM-Expanded Streptococcus thermophilus Cas9 C-to-T and C-to-G Base Editors for Programmable Base Editing
Hongyuan Zhang, Yifei Zhang, Wei-Xiao Wang, Weizhong Chen, Xia Zhang, Xingxu Huang, Wei Chen, Quanjiang Ji
Journal Article
Simultaneous saccharification and fermentation of wheat bran flour into ethanol using coculture of amylotic
Manikandan, T. Viruthagiri
Journal Article